Publications

Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1.

Author(s): Pandey M, Tuncman G, Hotamisligil GS, Samad F|Journal: Am J Pathol|PMID: 12598326| March 2003

Tumor necrosis factor-alpha (TNF-alpha) is elevated in obesity and in acute inflammatory states, and contributes to the elevated plasminogen activator…

A central role for JNK in obesity and insulin resistance.

Author(s): Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS|Journal: Nature|PMID: 12447443| November 2002

Obesity is closely associated with insulin resistance and establishes the leading risk factor for type 2 diabetes mellitus, yet the…