Dr. Hui’s research focuses on understanding metabolism with a quantitative and systems approach. Specifically, he integrates isotope tracing, mass spectrometry, and quantitative modeling to determine metabolic fluxes in important animal models. Fluxes are the most fundamental functional property of metabolism. Their systematic quantification holds the potential to understand important metabolic diseases. With this approach, Dr. Hui will focus on diseases with altered energy metabolism, including obesity and cachexia, with the long- term goal of revealing the mechanisms of body weight control and developing treatment strategies for these diseases.
Dr. Hui received a BSc and an MPhil in Physics, both from Hong Kong Baptist University, and a PhD in Biophysics from the University of California, San Diego. He completed postdoctoral work in the Lewis-Sigler Institute for Integrative Genomics at Princeton University. Dr. Hui is the recipient of a Pathway to Independence Award from the National Institutes of Health.