Publications – The Hotamışlıgil Lab at the Sabri Ülker Center

Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.

Author(s): Kars M, Yang L., Gregor MF, Mohammed BS, Pietka TA, Finck BN, Patterson BW, Horton JD, Mittendorfer B, Hotamisligil GS, Klein SJournal: DiabetesPMID: 20522594 August 2010

Insulin resistance is commonly associated with obesity. Studies conducted in obese mouse models found that endoplasmic reticulum (ER) stress contributes…

Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss.

Author(s): Gregor MF, Yang L., Fabbrini E, Mohammed BS, Eagon JC, Hotamisligil GS, Klein SJournal: DiabetesPMID: 19066313 March 2009

Obesity is associated with insulin resistance and type 2 diabetes, although the mechanisms linking these pathologies remain undetermined. Recent studies…