CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. Author(s): Chavey C, Lazennec G, Lagarrigue S, Clapé C, Iankova I, Teyssier J, Annicotte JS, Schmidt J, Mataki C, Yamamoto H, Sanches R, Guma A, Stich V, Vitkova M, Jardin-Watelet B, Renard E, Strieter R, Tuthill A, Hotamisligil GS, Vidal-Puig A, Zorzano A, Langin D, Fajas L|Journal: Cell Metab|PMID: 19356715| April 2009 We show here high levels of expression and secretion of the chemokine CXC ligand 5 (CXCL5) in the macrophage fraction…
SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice. Author(s): Emanuelli B, Peraldi P, Filloux C, Chavey C, Freidinger K, Hilton DJ, Hotamisligil GS, Van Obberghen E|Journal: J Biol Chem|PMID: 11604392| December 2001 SOCS (suppressor of cytokine signaling) proteins are inhibitors of cytokine signaling involved in negative feedback loops. We have recently shown…
