Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Author(s): Furuhashi M, Tuncman G, Gorgun CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS|Journal: Nature|PMID: 17554340| June 2007 Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient…
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Author(s): Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, Uysal KT, Cao Q, Atsumi G, Malone H, Krishnan B, Minokoshi Y, Kahn BB, Parker RA, Hotamisligil GS|Journal: Cell Metab|PMID: 16054052| February 2005 Fatty acid binding proteins (FABPs) are cytosolic fatty acid chaperones whose biological role and mechanisms of action are not well…