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Publications

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A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease.

Author(s): Tuncman G, Erbay E, Hom X, De Vivo I, Campos H, Rimm EB, Hotamisligil GS|Journal: Proc Natl Acad Sci U S A|PMID: 16641093| May 2006
Obesity and the associated pathologies including dyslipidemia, insulin resistance, type 2 diabetes, and cardiovascular disease constitute a major threat to…

Association between dietary factors and plasma adiponectin concentrations in men.

Author(s): Pischon T, Girman CJ, Rifai N, Hotamisligil GS, Rimm EB|Journal: Am J Clin Nutr|PMID: 15817852| April 2005
Adiponectin, an adipocyte-derived peptide, improves insulin sensitivity, has antiinflammatory and antiatherogenic effects, and is associated with a lower risk of…

Plasma adiponectin levels and risk of myocardial infarction in men.

Author(s): Pischon T, Girman CJ, Hotamisligil GS, Rifai N, Hu FB, Rimm EB|Journal: JAMA|PMID: 15082700| April 2004
Adiponectin, a recently discovered adipocyte-derived peptide, is involved in the regulation of insulin sensitivity and lipid oxidation and, purportedly, in…

Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers.

Author(s): Pischon T, Hankinson SE, Hotamisligil GS, Rifai N, Rimm EB|Journal: Obes Res|PMID: 12972675| September 2003
This study investigated the relationship between physical activity and the obesity-related inflammatory markers C-reactive protein, interleukin-6, and soluble tumor necrosis…

Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women.

Author(s): Pischon T, Hankinson SE, Hotamisligil GS, Rifai N, Willett WC, Rimm EB|Journal: Circulation|PMID: 12821543| July 2003
Polyunsaturated fatty acid intake favorably affects chronic inflammatory-related diseases such as cardiovascular disease; however, high intake of n-6 fatty acids…

Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year.

Author(s): Pischon T, Hotamisligil GS, Rimm EB|Journal: Clin Chem|PMID: 12651819| April 2003

Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men.

Author(s): Chu NF, Spiegelman D, Hotamisligil GS, Rifai N, Stampfer M, Rimm EB|Journal: Atherosclerosis|PMID: 11472752| August 2001
Obesity is related to cardiovascular disease (CVD) morbidity and mortality, however, the mechanisms for the development of obesity-induced CVD risk…

Plasma leptin concentrations and four-year weight gain among US men.

Author(s): Chu NF, Spiegelman D, Yu J, Rifai N, Hotamisligil GS, Rimm EB|Journal: Int J Obes Relat Metab Disord|PMID: 11319631| March 2001
Leptin, a primarily adipose tissue-derived protein product of the obesity (ob) gene, is an important regulator of energy metabolism. The…

Dietary and lifestyle factors in relation to plasma leptin concentrations among normal weight and overweight men.

Author(s): Chu NF, Stampfer MJ, Spiegelman D, Rifai N, Hotamisligil GS, Rimm EB|Journal: Int J Obes Relat Metab Disord|PMID: 11244465| January 2001
Leptin, the product of the obesity (ob) gene, is a multi-functional polypeptide that is important in energy metabolism, which is…

Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men.

Author(s): Chu NF, Spiegelman D, Rifai N, Hotamisligil GS, Rimm EB|Journal: Int J Obes Relat Metab Disord|PMID: 11033975| September 2000
Leptin, an adipocyte-derived protein product of the obesity (ob) gene, is a multifunctional polypeptide associated with the development of obesity-related…

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