Publications

Regulation of adiponectin in adipocytes upon exposure to HIV-1.

Author(s): Sankalé JL, Tong Q, Hadigan CM, Tan G, Grinspoon SK, Kanki PJ, Hotamisligil GS|Journal: HIV Med|PMID: 16630040| May 2006

Adipose dysregulation, dyslipidemia, and insulin resistance are hallmarks of HIV-related lipodystrophy. The precise mechanisms behind these disturbances are unknown. In…

The transcription factor GATA2 regulates differentiation of brown adipocytes.

Author(s): Tsai J, Tong Q, Tan G, Chang AN, Orkin SH, Hotamisligil GS|Journal: EMBO Rep|PMID: 16082385| September 2005

Brown adipose tissue (BAT) is a specialized mammalian tissue and a site of adaptive thermogenesis. Although the metabolic functions of…

Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation.

Author(s): Tong Q, Tsai J, Tan G, Dalgin G, Hotamisligil GS|Journal: Mol Cell Biol|PMID: 15632071| January 2005

We have previously demonstrated that GATA-2 and GATA-3 are expressed in adipocyte precursors and control the preadipocyte-to-adipocyte transition. Constitutive expression…

Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices.

Author(s): Tong Q, Sankalé JL, Hadigan CM, Tan G, Rosenberg ES, Kanki PJ, Grinspoon SK, Hotamisligil GS|Journal: J Clin Endocrinol Metab|PMID: 12679439| April 2003

HIV-related lipodystrophy is characterized by adipose redistribution, dyslipidemia, and insulin resistance. Adiponectin is an adipose-derived peptide thought to act as…