Publications – The Hotamışlıgil Lab at the Sabri Ülker Center

Autoamplification of tumor necrosis factor-alpha: a potential mechanism for the maintenance of elevated tumor necrosis factor-alpha in male but not female obese mice.

Author(s): Neels JG, Pandey M, Hotamisligil GS, Samad FJournal: Am J PatholPMID: 16436658 February 2006

Although tumor necrosis factor-alpha (TNF-alpha) is elevated in adipose tissue in obesity and may contribute to the cardiovascular and metabolic…

Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1.

Author(s): Pandey M, Tuncman G, Hotamisligil GS, Samad FJournal: Am J PatholPMID: 12598326 March 2003

Tumor necrosis factor-alpha (TNF-alpha) is elevated in obesity and in acute inflammatory states, and contributes to the elevated plasminogen activator…

Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1.

Author(s): Samad F, Uysal KT, Wiesbrock SM, Pandey M, Hotamisligil GS, Loskutoff DJJournal: Proc Natl Acad Sci U S APMID: 10359811 June 1999

Obesity is associated with a cluster of abnormalities, including hypertension, insulin resistance, hyperinsulinemia, and elevated levels of both plasminogen activator…