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Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research
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Publications

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Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein.

Author(s): Hotamisligil GS, Johnson RS, Distel RJ, Ellis R, Papaioannou VE, Spiegelman BM|Journal: Science|PMID: 8910278| November 1996
Fatty acid binding proteins (FABPs) are small cytoplasmic proteins that are expressed in a highly tissue-specific manner and bind to…

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance.

Author(s): Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM|Journal: Science|PMID: 8571133| February 1996
Tumor necrosis factor-alpha (TNF-alpha) is an important mediator of insulin resistance in obesity and diabetes through its ability to decrease…
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