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Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research
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Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.

Author(s): Charles KN, Li MD, Engin F, Arruda AP, Inouye K, Hotamisligil GS|Journal: Cell Rep|PMID: 29020626| October 2017
Deterioration of metabolic health is a hallmark of aging and generally assumed to be detrimental to longevity. Exposure to a…

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis.

Author(s): Erbay E, Babaev VR, Mayers JR, Makowski L, Charles KN, Snitow ME, Fazio S, Wiest MM, Watkins SM, Linton MF, Hotamisligil GS|Journal: Nat Med|PMID: 19966778| December 2009
Macrophages show endoplasmic reticulum (ER) stress when exposed to lipotoxic signals associated with atherosclerosis, although the pathophysiological importance and the…
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