Publications

Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages.

Author(s): Zhou Y, Yu X, Chen H, Sjöberg S, Roux J, Zhang L, Ivoulsou AH, Bensaid F, Liu CL, Liu J, Tordjman J, Clement K, Lee CH, Hotamisligil GS, Libby P, Shi GP|Journal: Cell Metab|PMID: 26481668| December 2015

Mast cells (MCs) contribute to the pathogenesis of obesity and diabetes. This study demonstrates that leptin deficiency slants MCs toward…

Interaction of tumor necrosis factor-alpha- and thiazolidinedione-regulated pathways in obesity.

Author(s): Wellen KE, Uysal KT, Wiesbrock S, Yang Q, Chen H, Hotamisligil GS|Journal: Endocrinology|PMID: 14764635| May 2004

Thiazolidinediones (TZDs) are potent insulin-sensitizing compounds and high-affinity ligands for the transcription factor peroxisomal proliferator-activated receptor gamma. The mechanism through…