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Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research
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Publications

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A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use.

Author(s): Liu S, Brown JD, Stanya KJ, Homan E, Leidl M, Inouye K, Bhargava P, Gangl MR, Dai L, Hatano B, Hotamisligil GS, Saghatelian A, Plutzky J, Lee CH|Journal: Nature|PMID: 24153306| October 2013
Food intake increases the activity of hepatic de novo lipogenesis, which mediates the conversion of glucose to fats for storage…

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.

Author(s): Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee CH, Manning BD|Journal: Cell Metab|PMID: 21723501| July 2011
Through unknown mechanisms, insulin activates the sterol regulatory element-binding protein (SREBP1c) transcription factor to promote hepatic lipogenesis. We find that…

A prospective study of inflammatory cytokines and diabetes mellitus in a multiethnic cohort of postmenopausal women.

Author(s): Liu S, Tinker L, Song Y, Rifai N, Bonds DE, Cook NR, Heiss G, Howard BV, Hotamisligil GS, Hu FB, Kuller LH, Manson JE|Journal: Arch Intern Med|PMID: 17698692| August 2007
Inflammatory cytokines, including tumor necrosis factor alpha, IL-6 (interleukin 6), and high-sensitivity C-reactive protein (hsCRP), have been related to both…

Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women.

Author(s): Song Y, Manson JE, Tinker L, Rifai N, Cook NR, Hu FB, Hotamisligil GS, Ridker PM, Rodriguez BL, Margolis KL, Oberman A, Liu S|Journal: Diabetes|PMID: 17389327| July 2007
Elevated circulating levels of soluble adhesion molecules as markers of endothelial dysfunction have been related to insulin resistance and its…
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