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Publications

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Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

Author(s): Cao H, Sekiya M, Ertunc ME, Burak MF, Mayers JR, White A, Inouye K, Rickey LM, Ercal BC, Furuhashi M, Tuncman G, Hotamisligil GS|Journal: Cell Metab|PMID: 23663740| May 2013
Proper control of hepatic glucose production is central to whole-body glucose homeostasis, and its disruption plays a major role in…

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis.

Author(s): Erbay E, Babaev VR, Mayers JR, Makowski L, Charles KN, Snitow ME, Fazio S, Wiest MM, Watkins SM, Linton MF, Hotamisligil GS|Journal: Nat Med|PMID: 19966778| December 2009
Macrophages show endoplasmic reticulum (ER) stress when exposed to lipotoxic signals associated with atherosclerosis, although the pathophysiological importance and the…

Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism.

Author(s): Cao H, Gerhold K, Mayers JR, Wiest MM, Watkins SM, Hotamisligil GS|Journal: Cell|PMID: 18805087| September 2008
Dysregulation of lipid metabolism in individual tissues leads to systemic disruption of insulin action and glucose metabolism. Utilizing quantitative lipidomic…
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