Author(s): Cao H, Sekiya M, Ertunc ME, Burak MF, Mayers JR, White A, Inouye K, Rickey LM, Ercal BC, Furuhashi M, Tuncman G, Hotamisligil GS|Journal: Cell Metab|PMID:23663740| May 2013
Proper control of hepatic glucose production is central to whole-body glucose homeostasis, and its disruption plays a major role in…
Author(s): Erbay E, Babaev VR, Mayers JR, Makowski L, Charles KN, Snitow ME, Fazio S, Wiest MM, Watkins SM, Linton MF, Hotamisligil GS|Journal: Nat Med|PMID:19966778| December 2009
Macrophages show endoplasmic reticulum (ER) stress when exposed to lipotoxic signals associated with atherosclerosis, although the pathophysiological importance and the…
Author(s): Cao H, Gerhold K, Mayers JR, Wiest MM, Watkins SM, Hotamisligil GS|Journal: Cell|PMID:18805087| September 2008
Dysregulation of lipid metabolism in individual tissues leads to systemic disruption of insulin action and glucose metabolism. Utilizing quantitative lipidomic…