A hormone complex of FABP4 and nucleoside kinases regulates islet function.

Author(s): Prentice KJ, Saksi J, Robertson LT, Lee GY, Inouye KE, Eguchi K, Lee A, Cakici O, Otterbeck E, Cedillo P, Achenbach P, Ziegler AG, Calay ES, Engin F, Hotamisligil GSJournal: NaturePMID: 34880500 December 2021
The liberation of energy stores from adipocytes is critical to support survival in times of energy deficit; however, uncontrolled or…

TMEM2 Modulates ER Stress in a Non-canonical Manner.

Author(s): Goncalves RLS, Hotamisligil GSJournal: Cell MetabPMID: 31801059 December 2019
Cells utilize multiple mechanisms to support endoplasmic reticulum (ER) function. The unfolded protein response, UPR, is engaged during proteotoxic challenges…