Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion. Author(s): Lee AH, Heidtman K, Hotamisligil GS, Glimcher LH|Journal: Proc Natl Acad Sci U S A|PMID: 21555585| May 2011 As a key regulator of the unfolded protein response, the transcription factor XBP1 activates genes in protein secretory pathways and…
