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Publications

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Endoplasmic reticulum stress and atherosclerosis.

Author(s): Hotamisligil GS|Journal: Nat Med|PMID: 20376052| April 2010
Atherosclerosis and related cardiovascular diseases represent one of the greatest threats to human health worldwide. Despite important progress in prevention…

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease.

Author(s): Hotamisligil GS|Journal: Cell|PMID: 20303879| March 2010
The endoplasmic reticulum (ER) is the major site in the cell for protein folding and trafficking and is central to…

Inflammation and endoplasmic reticulum stress in obesity and diabetes.

Author(s): Hotamisligil GS|Journal: Int J Obes (Lond)|PMID: 19136991| December 2008
Obesity is associated with chronic low-grade inflammation. Inflammatory signals interfere with insulin action and disrupt metabolic homeostasis. The c-Jun N-terminal…
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