Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. Author(s): Baumgartl J, Baudler S, Scherner M, Babaev V, Makowski L, Suttles J, McDuffie M, Tobe K, Kadowaki T, Fazio S, Kahn CR, Hotamisligil GS, Krone W, Linton M, Brüning JC|Journal: Cell Metab|PMID: 16581002| April 2006 Inflammatory processes play an important role in the pathogenesis of vascular diseases, and insulin-resistant diabetes mellitus type 2 represents an…
The role of fatty acid binding proteins in metabolic syndrome and atherosclerosis. Author(s): Makowski L, Hotamisligil GS|Journal: Curr Opin Lipidol|PMID: 16148539| October 2005 The global prevalence of obesity is increasing epidemically. Obesity causes an array of health problems, reduces life expectancy, and costs…
The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities. Author(s): Makowski L, Brittingham KC, Reynolds JM, Suttles J, Hotamisligil GS|Journal: J Biol Chem|PMID: 15684432| April 2005 Fatty acid-binding proteins are cytosolic fatty acid chaperones, and the adipocyte isoform, aP2, plays an important role in obesity and…
