Upregulation of uncoupling protein 2 mRNA in genetic obesity: lack of an essential role for leptin, hyperphagia, increased tissue lipid content, and TNF-alpha. Author(s): Memon RA, Hotamisligil GS, Wiesbrock SM, Uysal KT, Faggioni R, Moser AH, Feingold KR, Grunfeld C|Journal: Biochim Biophys Acta|PMID: 10685029| February 2000 Uncoupling protein 2 (UCP2) has been proposed to play a prominent role in the regulation of energy balance. UCP2 mRNA…
Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity. Author(s): Uysal KT, Wiesbrock SM, Hotamisligil GS|Journal: Endocrinology|PMID: 9832419| December 1998 Although obesity has become the most common metabolic disorder in the developed world and is highly associated with insulin resistance…