Potential role for snoRNAs in PKR activation during metabolic stress. Author(s): Youssef OA, Safran SA, Nakamura T, Nix DA, Hotamisligil GS, Bass BL|Journal: Proc Natl Acad Sci U S A|PMID: 25848059| April 2015 Protein kinase RNA-activated (PKR) has long been known to be activated by viral double-stranded RNA (dsRNA) as part of the…
A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2α phosphorylation in obesity. Author(s): Nakamura T, Kunz RC, Zhang C, Kimura T, Yuan CL, Baccaro B, Namiki Y, Gygi SP, Hotamisligil GS|Journal: Cell Rep|PMID: 25843719| April 2015 Aberrant stress and inflammatory responses are key factors in the pathogenesis of obesity and metabolic dysfunction, and the double-stranded RNA-dependent…
