Skip to content
  • Donate
Follow:
Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research
  • About
    • About the Center
      • Announcement of the Sabri Ülker Center’s Inaguration
      • About Sabri Ülker
      • Our First Ülker Fellows
    • Annual Reports
    • Contact
    • Donate
  • Research
    • Organelle Homeostasis
    • Lipid Metabolism
    • Sabri Ülker Center Research Facilities
    • Publications
      • Representative Publications
      • Bibliography
  • People
    • Lab Members
    • Lab Alumni
    • Lab Life
  • Events
    • Sabri Ülker Symposium
    • Science Award
  • News
  • Career

Publications

Filter Results

Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity.

Author(s): Arruda AP, Pers BM, Parlakgül G, Güney E, Inouye K, Hotamisligil GS|Journal: Nat Med|PMID: 25419710| December 2014
Proper function of the endoplasmic reticulum (ER) and mitochondria is crucial for cellular homeostasis, and dysfunction at either site has…

Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

Author(s): Cao H, Sekiya M, Ertunc ME, Burak MF, Mayers JR, White A, Inouye K, Rickey LM, Ercal BC, Furuhashi M, Tuncman G, Hotamisligil GS|Journal: Cell Metab|PMID: 23663740| May 2013
Proper control of hepatic glucose production is central to whole-body glucose homeostasis, and its disruption plays a major role in…

Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting.

Author(s): Fu S, Fan J, Blanco J, Gimenez-Cassina A, Danial NN, Watkins SM, Hotamisligil GS|Journal: PLoS Genet|PMID: 22927828| August 2012
Obesity-associated metabolic complications are generally considered to emerge from abnormalities in carbohydrate and lipid metabolism, whereas the status of protein…

Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress.

Author(s): Oh RS, Pan WC, Yalcin A, Zhang H, Guilarte TR, Hotamisligil GS, Christiani DC, Lu Q|Journal: J Biol Chem|PMID: 22215663| February 2012
Exposure to the toxic metalloid arsenic is associated with diabetes and cancer and causes proteotoxicity and endoplasmic reticulum (ER) stress…

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity.

Author(s): Fu S, Yang L., Li P, Hofmann O, Dicker L, Hide W, Lin X, Watkins SM, Ivanov AR, Hotamisligil GS|Journal: Nature|PMID: 21532591| May 2011
The endoplasmic reticulum (ER) is the main site of protein and lipid synthesis, membrane biogenesis, xenobiotic detoxification and cellular calcium…
Harvard T.H. Chan School of Public Health
677 Huntington Avenue Boston, MA 02115
+1 (617) 495‑1000
  • Harvard Chan Home
  • Contact Us
  • Harvard University Home
  • Make a Gift
  • Privacy Policy
  • Report Copyright Violation
  • Accessibility
Copyright © The President and Fellows of Harvard College