Publications

Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production.

Author(s): Cao H, Sekiya M, Ertunc ME, Burak MF, Mayers JR, White A, Inouye K, Rickey LM, Ercal BC, Furuhashi M, Tuncman G, Hotamisligil GS|Journal: Cell Metab|PMID: 23663740| May 2013

Proper control of hepatic glucose production is central to whole-body glucose homeostasis, and its disruption plays a major role in…

Nutrient sensing and inflammation in metabolic diseases.

Author(s): Hotamisligil GS, Erbay E|Journal: Nat Rev Immunol|PMID: 19029988| December 2008

The proper functioning of the pathways that are involved in the sensing and management of nutrients is central to metabolic…

The transcription factor GATA2 regulates differentiation of brown adipocytes.

Author(s): Tsai J, Tong Q, Tan G, Chang AN, Orkin SH, Hotamisligil GS|Journal: EMBO Rep|PMID: 16082385| September 2005

Brown adipose tissue (BAT) is a specialized mammalian tissue and a site of adaptive thermogenesis. Although the metabolic functions of…

Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation.

Author(s): Tong Q, Tsai J, Tan G, Dalgin G, Hotamisligil GS|Journal: Mol Cell Biol|PMID: 15632071| January 2005

We have previously demonstrated that GATA-2 and GATA-3 are expressed in adipocyte precursors and control the preadipocyte-to-adipocyte transition. Constitutive expression…