Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases. Author(s): Engin F, Hotamisligil GS|Journal: Diabetes Obes Metab|PMID: 21029307| October 2010 The endoplasmic reticulum (ER) is a eukaryotic organelle that plays important roles in protein synthesis, folding and trafficking, calcium homoeostasis…