Publications – The Hotamışlıgil Lab at the Sabri Ülker Center

Inflammatory pathways and insulin action.

Author(s): Hotamisligil GSJournal: Int J Obes Relat Metab DisordPMID: 14704746 December 2003

Obesity and type 2 diabetes are associated with a state of abnormal inflammatory response. While this correlation has also been…

Effects of obesity and weight loss on the expression of proteins involved in fatty acid metabolism in human adipose tissue.

Author(s): Fisher RM, Hoffstedt J, Hotamisligil GS, Thörne A, Rydén MJournal: Int J Obes Relat Metab DisordPMID: 12355335 October 2002

Disturbances in adipocyte lipolysis in obesity may contribute to elevated circulating non-esterified fatty acid (NEFA) concentrations and insulin resistance. In…

Plasma leptin concentrations and four-year weight gain among US men.

Author(s): Chu NF, Spiegelman D, Yu J, Rifai N, Hotamisligil GS, Rimm EBJournal: Int J Obes Relat Metab DisordPMID: 11319631 March 2001

Leptin, a primarily adipose tissue-derived protein product of the obesity (ob) gene, is an important regulator of energy metabolism. The…

Dietary and lifestyle factors in relation to plasma leptin concentrations among normal weight and overweight men.

Author(s): Chu NF, Stampfer MJ, Spiegelman D, Rifai N, Hotamisligil GS, Rimm EBJournal: Int J Obes Relat Metab DisordPMID: 11244465 January 2001

Leptin, the product of the obesity (ob) gene, is a multi-functional polypeptide that is important in energy metabolism, which is…

Molecular mechanisms of insulin resistance and the role of the adipocyte.

Author(s): Hotamisligil GSJournal: Int J Obes Relat Metab DisordPMID: 11126235 November 2000

Insulin resistance is a common feature of obesity and predisposes the affected individuals to a variety of diseases, including hypertension,…

Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men.

Author(s): Chu NF, Spiegelman D, Rifai N, Hotamisligil GS, Rimm EBJournal: Int J Obes Relat Metab DisordPMID: 11033975 September 2000

Leptin, an adipocyte-derived protein product of the obesity (ob) gene, is a multifunctional polypeptide associated with the development of obesity-related…