Sympathetic tone dictates the impact of lipolysis on FABP4 secretion. Author(s): Prentice KJ, Lee A, Cedillo P, Inouye KE, Ertunc ME, Riveros JK, Lee GY, Hotamisligil GS|Journal: J Lipid Res|PMID: 37172691| July 2023 Levels of circulating FABP4 protein are strongly associated with obesity and metabolic disease in both mice and humans, and secretion…
Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses. Author(s): Prentice KJ, Saksi J, Hotamisligil GS|Journal: J Lipid Res|PMID: 30705117| April 2019 Although counterregulatory hormones and mediators of the fight-or-flight responses are well defined at many levels, how energy stores per se…
Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment. Author(s): Ertunc ME, Hotamisligil GS|Journal: J Lipid Res|PMID: 27330055| December 2016 Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids, and triglycerides. These molecules represent a highly…
Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity. Author(s): Ertunc ME, Sikkeland J, Fenaroli F, Griffiths G, Daniels MP, Cao H, Saatcioglu F, Hotamisligil GS|Journal: J Lipid Res|PMID: 25535287| February 2015 Adipocyte fatty acid binding protein 4, aP2, contributes to the pathogenesis of several common diseases including type 2 diabetes, atherosclerosis,…
Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. Author(s): Gregor MF, Hotamisligil GS|Journal: J Lipid Res|PMID: 17699733| September 2007 In the context of obesity and its related maladies, the adipocyte plays a central role in the balance, or imbalance,…
