Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses. Author(s): Prentice KJ, Saksi J, Hotamisligil GS|Journal: J Lipid Res|PMID: 30705117| April 2019 Although counterregulatory hormones and mediators of the fight-or-flight responses are well defined at many levels, how energy stores per se…
Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment. Author(s): Ertunc ME, Hotamisligil GS|Journal: J Lipid Res|PMID: 27330055| December 2016 Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids, and triglycerides. These molecules represent a highly…
Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity. Author(s): Ertunc ME, Sikkeland J, Fenaroli F, Griffiths G, Daniels MP, Cao H, Saatcioglu F, Hotamisligil GS|Journal: J Lipid Res|PMID: 25535287| February 2015 Adipocyte fatty acid binding protein 4, aP2, contributes to the pathogenesis of several common diseases including type 2 diabetes, atherosclerosis,…
Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. Author(s): Gregor MF, Hotamisligil GS|Journal: J Lipid Res|PMID: 17699733| September 2007 In the context of obesity and its related maladies, the adipocyte plays a central role in the balance, or imbalance,…
