Publications

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Author(s): Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GSJournal: Nat MedPMID: 29400713 March 2018

Adipocytes possess remarkable adaptive capacity to respond to nutrient excess, fasting or cold exposure, and they are thus an important…

Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.

Author(s): Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YHJournal: Nat MedPMID: 29117173 November 2017

This corrects the article DOI: 10.1038/nm.4297.

The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.

Author(s): Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YHJournal: Nat MedPMID: 28346411 May 2017

Brown adipose tissue (BAT) and beige adipose tissue combust fuels for heat production in adult humans, and so constitute an…

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.

The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.

Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity.

Turning off the inflammatory, but not the metabolic, flames.

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.

Linking the inflammasome to obesity-related disease.

Endoplasmic reticulum stress and atherosclerosis.

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis.

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.