Annual Report 2018

The 2018 report offers some highlights of the work completed by our laboratory and to share a few exciting developments that are in progress at the Center, including this year’s Sabri Ülker Center Symposium on Metabolism and Life.

2018 EASD–Novo Nordisk Foundation Diabetes Prize for Excellence

Congratulations to Gökhan Hotamışlıgil for receiving this year’s 2018 EASD–Novo Nordisk Foundation Diabetes Prize for Excellence! Professor Gökhan Hotamışlıgil receives the 2018 EASD–Novo Nordisk Foundation Diabetes Prize for Excellence accompanied by DKK 6 million (€806,000) for his outstanding research efforts over the past 25 years that have led to groundbreaking new knowledge about the relationship between obesity and diabetes and potential paths for treatment. Chronic metabolic diseases such as obesity and diabetes…

Congratulations Dr. Lauren Robertson and Dr. Mustafa Yilmaz!

Congratulations to our newest PhD graduates — Dr. Lauren Robertson and Dr. Mustafa Yilmaz! Dr. Robertson is a graduate of Smith College and joined the lab as a graduate student in 2013. Dr. Yilmaz has been with the lab since 2012, following a degree from Bilkent University. We wish you all the best in your next chapters and cannot wait to see what the future holds!

Brown fat waste disposal facilities keeps you warm, healthy, and metabolically mighty

Researchers from the Hotamışlıgil Lab and the Sabri Ülker Center at Harvard T.H. Chan School of Public Health have observed that one key adaptive response in the brown adipose tissue is through protein degradation, or simply put; eliminate cellular waste.  The scientists also identified that this critical response system is operated by a molecular switch known as NRF1 that responds to cold or other activating signals to turn on the disposal…

Molecular guardian defends cells, organs against excess cholesterol

A team of researchers at the Harvard T.H. Chan School of Public Health has illuminated a critical player in cholesterol metabolism that acts as a molecular guardian in cells to help maintain cholesterol levels within a safe, narrow range. Known as Nrf1, it both senses and responds to excess cholesterol, and could represent a potential new therapeutic target in a multitude of diseases where cholesterol metabolism is disrupted. The study…