Inflammation, metaflammation, and immunometabolic disorders

This page contains supplemental materials for the papers entitled ”Inflammation, metaflammation, and immunometabolic disorders” and “Foundations of immunometabolism and implications for metabolic health and disease” by Gokhan Hotamisligil, MD, PhD

Read the full paper: Nature 542, 177-185 (09 February 2017)



Immune signals and their receptors

Supplemental Figure 1: Immune signals and their receptors with described effects on metabolism

Metabolic Effects of IL-6

The metabolic effects of IL-6 are pleiotropic and context dependent, leading to numerous, highly-reproduced studies indicating both positive and negative outcomes.

Metabolic and Immunological Roles of Major Kinase Pathways